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51st ERA-EDTA CONGRESS

 

31 May - 3 June 2014 AMSTERDAM
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Discussion forum - 51st ERA-EDTA CONGRESS
    Topic - F) Hypertension.

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Poster: 30
Visits: 27
Title: URINARY ALBUMIN EXCRETION, BLOOD PRESSURE CHANGES AND HYPERTENSION INCIDENCE IN THE COMMUNITY: EFFECT MODIFICATION BY KIDNEY FUNCTION
Authors: Hong Xu ,
Centre: Karolinska instituet

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URINARY ALBUMIN EXCRETION, BLOOD PRESSURE CHANGES AND HYPERTENSION INCIDENCE IN THE COMMUNITY: EFFECT MODIFICATION BY KIDNEY FUNCTION

Hong Xu
Thread initiator
Subspeciality
Reg: 5/6/2014 5:48:00 PM

Comment# 1

Both increased albuminuria and reduced kidney function may predict blood pressure (BP) progression in the community, while exacerbate each others effects.The main finding of our study is the longitudinal association between higher UAER and increase in ABPM and hypertension incidence in a cohort of community dwelling elderly men. Importantly, the presence of impaired renal function modified and exacerbated these associations. Although these results may be anticipated, the prognostic value of combining these two features has, to the best of knowledge, not been formally demonstrated before, while it agrees with the most recent KDIGO guidelines. Of additional interest, these associations were also evident at UAER levels below the current diagnostic threshold for microalbuminuria. Although observational in nature, our analysis refutes the notion that albuminuria should merely be considered as a consequence of long term poorly controlled hypertension and provides additional support for the

Comment added on 5/6/2014 5:48:00 PM 
     
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